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Veterinarian challenges miasma theory during 1872 Epizootic

bigthink.com · 11 September 2026
Veterinarian challenges miasma theory during 1872 Epizootic
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In 1872, James Law, a veterinarian in the United States, investigated the widespread horse flu known as the Great Epizootic, and used detailed data to argue against the prevailing miasma theory of disease.

Law meticulously examined meteorological data, geographical patterns, and symptoms in horses, finding no correlation between atmospheric conditions and the spread of the illness.

He gathered daily measurements of temperature, wind, and barometric pressure, comparing data from October 1872 to the previous 28 years, and found no unusual weather patterns during the outbreak. Law’s research led him to believe a specific contagion caused the disease, rather than “bad air,” and he focused on microscopic granules found in sick horses as the potential source.

While unable to directly observe a virus with the technology available, Law theorized that a “virulent principle” existed within these granules and rapidly multiplied within infected animals. Law published his 45-page report, “Influenza in Horses,” and a condensed version in The Lens, presenting his evidence and challenging the long-held belief in miasma theory. Though miasma theory didn't disappear immediately, Law’s data-driven approach helped shift the medical community toward accepting germ theory, influencing future practices like quarantine and disease control.

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